Assay Detail
Binding
CHEMBL654879
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested in vitro for inhibitory activity against Butyrylcholinesterase
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Acetylcholinesterase inhibition by tacrine analogues
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.66 | 7.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL95 | TACRINE | 4.0 | 1 | 7.26 |
| CHEMBL89012 | — | — | 1 | 5.93 |
| CHEMBL60167 | — | — | 1 | 5.33 |
| CHEMBL314800 | — | — | 1 | 5.31 |
| CHEMBL89011 | — | — | 1 | 5.18 |
| CHEMBL50608 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL95 | TACRINE | IC50 | = | 54.7 | nM | 7.26 |
| CHEMBL89012 | — | IC50 | = | 1180.0 | nM | 5.93 |
| CHEMBL60167 | — | IC50 | = | 4670.0 | nM | 5.33 |
| CHEMBL314800 | — | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL89011 | — | IC50 | = | 6580.0 | nM | 5.18 |
| CHEMBL50608 | — | IC50 | = | 12000.0 | nM | 4.92 |