Assay Detail
Functional
CHEMBL655309
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for anti-HIV activity in HIV -I Lai infected CEM-SS cells.
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CEM-SS |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis, mode of action, and biological activities of rebeccamycin bromo derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.03 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL51826 | — | — | 1 | 7.16 |
| CHEMBL3350557 | — | — | 1 | 6.80 |
| CHEMBL370100 | REBECCAMYCIN | — | 1 | 6.28 |
| CHEMBL52964 | — | — | 1 | 5.93 |
| CHEMBL3350560 | — | — | 1 | 5.40 |
| CHEMBL3350558 | — | — | 1 | 5.31 |
| CHEMBL3350564 | — | — | 1 | 5.31 |
| CHEMBL3350565 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL51826 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL3350557 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL370100 | REBECCAMYCIN | IC50 | = | 520.0 | nM | 6.28 |
| CHEMBL52964 | — | IC50 | = | 1170.0 | nM | 5.93 |
| CHEMBL3350560 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL3350558 | — | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL3350564 | — | IC50 | = | 4850.0 | nM | 5.31 |
| CHEMBL3350565 | — | IC50 | > | 1980.0 | nM | - |