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Assay Detail

CHEMBL655411

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The compound was evaluated for the cytotoxicity against CHO cells under hypoxic condition.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cricetulus griseus
Cell Type CHO
Confidence 1 — Organism
Curated By Intermediate

Target

CHO (CHEMBL613853)
Type CELL-LINE
Organism Cricetulus griseus

Publication

p-(Methylsulfinyl)phenyl nitrogen mustard as a novel bioreductive prodrug selective against hypoxic tumors.
Kwon CH, Blanco DR, Baturay N.
J Med Chem (1992) 35 : 2137 -2139
PubMed 1597864 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.05 4.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL66804 1 4.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL66804 IC50 = 90000.0 nM 4.05