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Assay Detail

CHEMBL655529

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of calmodulin-dependent PDE(3',5'-phosphodiesterase)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Phosphodiesterase 1 (CHEMBL2095150)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Inhibition of protein-protein association by small molecules: approaches and progress.
Toogood PL.
J Med Chem (2002) 45 : 1543 -1558
PubMed 11931608 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.88 8.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL43232 1 8.05
CHEMBL39285 1 7.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL43232 IC50 = 9.0 nM 8.05
CHEMBL39285 IC50 = 20.0 nM 7.70