Assay Detail
Functional
CHEMBL655541
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Compound was evaluated for antiviral activity against CEM SS cells infected with HIV-1(LAI strain).
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CEM-SS |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis of new non-nucleoside inhibitors of HIV-1
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.41 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL49171 | — | — | 1 | 6.00 |
| CHEMBL299397 | — | — | 1 | 5.52 |
| CHEMBL129 | ZIDOVUDINE | 4.0 | 1 | 5.52 |
| CHEMBL416107 | — | — | 1 | 5.22 |
| CHEMBL417909 | — | — | 1 | 5.10 |
| CHEMBL48516 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL49171 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL299397 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL129 | ZIDOVUDINE | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL416107 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL417909 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL48516 | — | IC50 | = | 8000.0 | nM | 5.10 |