Assay Detail
Functional
CHEMBL655581
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Tested for inhibition against CEM/MDR (multidrug resistant) cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CCRF-CEM |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design of antineoplastic agents on the basis of the "2-phenylnaphthalene-type" structural pattern. 2. Synthesis and biological activity studies of benzo]b]naphtho[2,3-d]furan-6,11-dione derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.72 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL541587 | — | — | 1 | 6.82 |
| CHEMBL542725 | — | — | 1 | 6.82 |
| CHEMBL544602 | — | — | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL541587 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL542725 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL544602 | — | IC50 | = | 300.0 | nM | 6.52 |