Assay Detail
Functional
CHEMBL655887
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In vitro cytotoxicity causing 50% growth inhibition was determined against C26-10 (murine colon carcinoma) cell line
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | Colon 26 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and in vitro cytotoxicity of novel long chain busulphan analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.37 | 4.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL169275 | — | — | 1 | 4.58 |
| CHEMBL169400 | — | — | 1 | 4.51 |
| CHEMBL820 | BUSULFAN | 4.0 | 1 | 4.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL169275 | — | IC50 | = | 26260.0 | nM | 4.58 |
| CHEMBL169400 | — | IC50 | = | 30970.0 | nM | 4.51 |
| CHEMBL820 | BUSULFAN | IC50 | = | 92500.0 | nM | 4.03 |