Assay Detail
Binding
CHEMBL656247
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Cholecystokinin type B receptor induced guinea pig gall bladder contractions when given intravenously
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Gastrin/cholecystokinin type B receptor (CHEMBL298) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
2002 Alfred Burger Award Address in Medicinal Chemistry. Natural products and design: interrelated approaches in drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.66 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL9387 | L-365260 | — | 1 | 8.70 |
| CHEMBL9506 | DEVAZEPIDE | 2.0 | 1 | 6.61 |
| CHEMBL357749 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL9387 | L-365260 | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL9506 | DEVAZEPIDE | IC50 | = | 245.0 | nM | 6.61 |
| CHEMBL357749 | — | IC50 | > | 100000.0 | nM | - |