Assay Detail
Functional
CHEMBL656276
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Concentration required to inhibit 50% of CEM cell lines
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CCRF-CEM |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Anti-human immunodeficiency and anti-hepatitis B virus activities of -l-2,3-dideoxy purine nucleosides
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.43 | 4.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL290427 | — | — | 1 | 4.43 |
| CHEMBL78101 | — | — | 1 | - |
| CHEMBL45071 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL290427 | — | IC50 | = | 37000.0 | nM | 4.43 |
| CHEMBL78101 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL45071 | — | IC50 | > | 10000.0 | nM | - |