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Assay Detail

CHEMBL656865

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound concentration which had a contractile effect on iris sphincter muscle of cats
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Felis catus
Tissue Sphincter muscle
Confidence 1 — Organism
Curated By Intermediate

Target

Felis catus (CHEMBL612670)
Type ORGANISM
Organism Felis catus

Publication

Phenyl-substituted prostaglandins: potent and selective antiglaucoma agents.
Resul B, Stjernschantz J, No K, Liljebris C, Selén G, Astin M, Karlsson M, Bito LZ.
J Med Chem (1993) 36 : 243 -248
PubMed 8423596 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 9.15 9.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1050 LATANOPROST ACID -1.0 1 9.15

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1050 LATANOPROST ACID EC50 = 0.71 nM 9.15