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Assay Detail

CHEMBL657029

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against Carbonic anhydrase IV
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Carbonic anhydrase 4 (CHEMBL281)
Type SINGLE PROTEIN
Organism Bos taurus

Publication

Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a bis-sulfonamide-two heads are better than one?
Casini A, Abbate F, Scozzafava A, Supuran CT.
Bioorg Med Chem Lett (2003) 13 : 2759 -2763
PubMed 12873509 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.89 7.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL51668 1 7.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL51668 Ki = 13.0 nM 7.89