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Assay Detail

CHEMBL657365

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was evaluated for the inhibition of binding of [125I]Bolton-Hunter CCK-8 to Cholecystokinin type A receptor in the rat pancreas.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Cholecystokinin receptor type A (CHEMBL2871)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Synthesis of a potent and selective non-peptide CCK-B/gastrin receptor antagonist tritiated ligand.
Hill D, Horwell D, Hunter J, Kneen C, Pritchard M, Suman-Chauhan N
Bioorg Med Chem Lett (1993) 3 : 885 -888
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.46 6.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL354049 1 6.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL354049 Ki = 350.0 nM 6.46