Assay Detail
Functional
CHEMBL657935
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Inhibition of cytopathic effect of HIV-1 RT containing the specified mutation K101E in CEM-SS cells.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CEM-SS |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel modifications in the alkenyldiarylmethane (ADAM) series of non-nucleoside reverse transcriptase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.34 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL107200 | — | — | 1 | 7.16 |
| CHEMBL294840 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL107200 | — | EC50 | = | 70.0 | nM | 7.16 |
| CHEMBL294840 | — | EC50 | = | 3050.0 | nM | 5.52 |