Assay Detail
Binding
CHEMBL657995
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Compound was evaluated for the competitive inhibition of [3H]3-(1,1-Dimethyl-heptyl)-9-hydroxymethyl-6,6-dimethyl-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-1-ol to cannabinoid receptor from synaptosomal membranes of rat whole brain
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
A novel probe for the cannabinoid receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 8.70 | 10.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL63818 | — | — | 1 | 10.35 |
| CHEMBL432107 | — | — | 1 | 9.74 |
| CHEMBL65475 | — | — | 1 | 9.72 |
| CHEMBL65192 | — | — | 1 | 8.70 |
| CHEMBL465 | DRONABINOL | 4.0 | 1 | 7.34 |
| CHEMBL65191 | — | — | 1 | 6.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL63818 | — | Ki | = | 0.045 | nM | 10.35 |
| CHEMBL432107 | — | Ki | = | 0.181 | nM | 9.74 |
| CHEMBL65475 | — | Ki | = | 0.19 | nM | 9.72 |
| CHEMBL65192 | — | Ki | = | 2.0 | nM | 8.70 |
| CHEMBL465 | DRONABINOL | Ki | = | 46.0 | nM | 7.34 |
| CHEMBL65191 | — | Ki | = | 466.0 | nM | 6.33 |