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Assay Detail

CHEMBL658028

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Binding
Inhibition of Cyclin-dependent kinase 2-cyclin A
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 6 — Multiple protein complex / RNA
Curated By Autocuration

Target

Cyclin-dependent kinase 2/cyclin A (CHEMBL2094128)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. Part 4: Heterocycles at C3.
Yue EW, DiMeo SV, Higley CA, Markwalder JA, Burton CR, Benfield PA, Grafstrom RH, Cox S, Muckelbauer JK, Smallwood AM, Chen H, Chang CH, Trainor GL, Seitz SP.
Bioorg Med Chem Lett (2004) 14 : 343 -346
PubMed 14698155 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.89 7.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL325023 1 7.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL325023 IC50 = 13.0 nM 7.89