Assay Detail
Functional
CHEMBL658312
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Evaluated for Biological activity, 50% effective concentration determined by its ability to produce cGMP
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Cell Type | CHO |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Designing analogues of mini atrial natriuretic peptide based on structural analysis by NMR and restrained molecular dynamics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 9.02 | 9.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2371608 | — | — | 1 | 9.75 |
| CHEMBL415834 | — | — | 1 | 8.88 |
| CHEMBL2371609 | — | — | 1 | 8.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2371608 | — | EC50 | = | 0.176 | nM | 9.75 |
| CHEMBL415834 | — | EC50 | = | 1.313 | nM | 8.88 |
| CHEMBL2371609 | — | EC50 | = | 3.76 | nM | 8.43 |