Assay Detail
Functional
CHEMBL658325
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Effective concentration of compound against HIV-1 infected CEM/O cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CCRF-CEM |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
ADA-Bypass by lipophilic cycloSal-ddAMP pro-nucleotides A second example of the efficiency of the cycloSal-Concept
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.77 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL40302 | — | — | 1 | 7.52 |
| CHEMBL289937 | — | — | 1 | 7.19 |
| CHEMBL416624 | — | — | 1 | 6.92 |
| CHEMBL23094 | — | — | 1 | 5.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL40302 | — | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL289937 | — | EC50 | = | 65.0 | nM | 7.19 |
| CHEMBL416624 | — | EC50 | = | 120.0 | nM | 6.92 |
| CHEMBL23094 | — | EC50 | = | 3670.0 | nM | 5.43 |