Assay Detail
Binding
CHEMBL658631
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Inhibitory concentration of compound against caspase-3
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Reducing the peptidyl features of caspase-3 inhibitors: a structural analysis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 7.48 | 9.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL443565 | — | — | 1 | 9.11 |
| CHEMBL420407 | — | — | 1 | 8.52 |
| CHEMBL81038 | — | — | 1 | 8.10 |
| CHEMBL1160520 | — | — | 1 | 8.04 |
| CHEMBL82932 | — | — | 1 | 7.75 |
| CHEMBL417149 | — | — | 1 | 7.36 |
| CHEMBL310554 | — | — | 1 | 5.76 |
| CHEMBL83964 | — | — | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL443565 | — | IC50 | = | 0.771 | nM | 9.11 |
| CHEMBL420407 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL81038 | — | IC50 | = | 7.95 | nM | 8.10 |
| CHEMBL1160520 | — | IC50 | = | 9.17 | nM | 8.04 |
| CHEMBL82932 | — | IC50 | = | 17.7 | nM | 7.75 |
| CHEMBL417149 | — | IC50 | = | 43.9 | nM | 7.36 |
| CHEMBL310554 | — | IC50 | = | 1735.0 | nM | 5.76 |
| CHEMBL83964 | — | IC50 | = | 6117.0 | nM | 5.21 |