Assay Detail
Binding
CHEMBL658968
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Binding affinity towards Cannabinoid receptor 2 in mouse spleen membranes
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Spleen |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel conformationally restricted tetracyclic analogs of delta8-tetrahydrocannabinol.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.44 | 9.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL67464 | — | — | 1 | 9.41 |
| CHEMBL303479 | — | — | 1 | 7.23 |
| CHEMBL63553 | — | — | 1 | 6.79 |
| CHEMBL66161 | — | — | 1 | 6.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL67464 | — | Ki | = | 0.39 | nM | 9.41 |
| CHEMBL303479 | — | Ki | = | 58.6 | nM | 7.23 |
| CHEMBL63553 | — | Ki | = | 161.5 | nM | 6.79 |
| CHEMBL66161 | — | Ki | = | 455.6 | nM | 6.34 |