Compound Detail
CHEMBL63553
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Basic Information
| ChEMBL ID | CHEMBL63553 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QZNJFXSEKJPBLV-LTGQRPFBSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
368.6
MW (Da)
6.69
ALogP
2
HBA
1
HBD
29.5
PSA (Ų)
0.47
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 6.79
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cannabinoid receptor 2 CHEMBL5373 | Ki | 6.79 | 6.79 | 161.5 | 1 |
| Cannabinoid receptor 1 CHEMBL3571 | Ki | 6.39 | 6.39 | 402.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cannabinoid receptor 2 | Ki | = | 161.5 | nM | 6.79 | Binding affinity towards Cannabinoid receptor 2 in mouse spleen membranes | 10465529 |
| Cannabinoid receptor 1 | Ki | = | 402.4 | nM | 6.39 | Binding affinity towards cannabinoid receptor 1 in rat forebrain membranes. | 10465529 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10465529 | 10.1016/s0960-894x(99)00355-8 | Cannabinoid receptor 1 | 1 |
| 10465529 | 10.1016/s0960-894x(99)00355-8 | Cannabinoid receptor 2 | 1 |
Data from ChEMBL 36 via Core Engine