Assay Detail
Functional
CHEMBL659126
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Cytotoxicity for relative cell viability compared to untreated control in CEF cells by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Gallus gallus |
| Cell Type | CEF |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel cationic transport agents for oligonucleotide delivery into primary leukemic cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.90 | 5.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL441617 | — | — | 1 | 5.07 |
| CHEMBL294514 | — | — | 1 | 5.00 |
| CHEMBL385213 | — | — | 1 | 5.00 |
| CHEMBL407898 | — | — | 1 | 5.00 |
| CHEMBL65606 | TMPYP4 | — | 1 | 4.82 |
| CHEMBL410693 | — | — | 1 | 4.82 |
| CHEMBL64624 | — | — | 1 | 4.82 |
| CHEMBL63095 | — | — | 1 | 4.70 |
| CHEMBL216608 | — | — | 1 | - |
| CHEMBL64170 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL441617 | — | IC50 | = | 8500.0 | nM | 5.07 |
| CHEMBL294514 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL385213 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL407898 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL65606 | TMPYP4 | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL410693 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL64624 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL63095 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL216608 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL64170 | — | IC50 | > | 20000.0 | nM | - |