Assay Detail

CHEMBL659462

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

cytotoxicity in CEM-SS cells by visual inspection

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

CCRF-CEM (CHEMBL382) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

CCRF-CEM (CHEMBL382) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target CCRF-CEM

CHEMBL382

Anchored from Assay target.

Protein identity CCRF-CEM

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	CCRF-CEM
Confidence	1 — Organism
Curated By	Intermediate

Target

CCRF-CEM (CHEMBL382) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Synthesis and antiproliferative and antiviral activity of 2'-deoxy-2'-fluoroarabinofuranosyl analogs of the nucleoside antibiotics toyocamycin and sangivamycin.

Krawczyk SH, Nassiri MR, Kucera LS, Kern ER, Ptak RG, Wotring LL, Drach JC, Townsend LB.
J Med Chem (1995) 38 : 4106 -4114
PubMed 7562946 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.40	6.40

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3143101	—	—	1	6.40

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3143101	—	IC50	=	400.0	nM	6.40