Assay Detail
Binding
CHEMBL659779
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of cyclin-dependent kinase activity of Cdc28p/CDK2p in Saccharomyces cerevisiae
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Cyclin-dependent kinase 1 (CHEMBL5213) ↗| Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
Publication
Borrelidin induces the transcription of amino acid biosynthetic enzymes via a GCN4-dependent pathway.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.62 | 4.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL70590 | BORRELIDIN | — | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL70590 | BORRELIDIN | IC50 | = | 24000.0 | nM | 4.62 |