Assay Detail
Binding
CHEMBL659780
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK4-Cyclin D
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Cyclin-dependent kinase 4/cyclin D (CHEMBL2095942) ↗| Type | PROTEIN COMPLEX GROUP |
| Organism | Homo sapiens |
Publication
1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases: highly potent 2,6-Difluorophenacyl analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.16 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL79049 | — | — | 1 | 6.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL79049 | — | IC50 | = | 690.0 | nM | 6.16 |