Cyclin-dependent kinase 4/cyclin D · PROTEIN COMPLEX GROUP · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P11802. Use UniProt P11802 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P11802 as the stable identity anchor, then attach disease evidence before program review.
Cyclin-dependent kinase 4
Review this target as Cyclin-dependent kinase 4/cyclin D, mapped to UniProt P11802. ChEMBL maps the protein component as Cyclin-dependent kinase 4. Sequence length is 303 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cyclin-dependent kinase 4/cyclin D as ChEMBL target CHEMBL2095942, mapped to UniProt P11802. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cyclin-dependent kinase 4/cyclin D |
| Target Type | PROTEIN COMPLEX GROUP |
| Organism | Homo sapiens |
| UniProt | P11802 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cyclin-dependent kinase 4 |
| UniProt Accession | P11802 |
| Component Type | Protein |
| Sequence Length | 303 aa |
Cyclin-dependent kinase 4
Review this target as Cyclin-dependent kinase 4/cyclin D, mapped to UniProt P11802. ChEMBL maps the protein component as Cyclin-dependent kinase 4. Sequence length is 303 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL142619 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL190281 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL365847 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL140808 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL141018 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL370295 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL426818 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL189937 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL190460 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL190627 | 8.3 | IC50 | 5.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 15 | 146 | 6.9 |