Assay Detail
Binding
CHEMBL660414
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Inhibitory effect on the activity of rat DNA polymerase beta was determined by inhibitory dose curves
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Biotinylated lithocholic acids for affinity chromatography of mammalian DNA polymerases alpha and beta.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.60 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3138225 | — | — | 1 | 4.96 |
| CHEMBL3138237 | — | — | 1 | 4.51 |
| CHEMBL3138247 | — | — | 1 | 4.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3138225 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL3138237 | — | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL3138247 | — | IC50 | = | 46000.0 | nM | 4.34 |