Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL660417

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition constant at a concentration of 5 uM on rat DNA polymerase beta as a function of nucleotide substrate concentration
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

DNA polymerase beta (CHEMBL4343)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Biotinylated lithocholic acids for affinity chromatography of mammalian DNA polymerases alpha and beta.
Watanabe M, Hanashima S, Mizushina Y, Yoshida H, Oshige M, Sakaguchi K, Sugawara F.
Bioorg Med Chem Lett (2002) 12 : 287 -290
PubMed 11814779 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.18 5.18

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3138225 1 5.18

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3138225 Ki = 6600.0 nM 5.18