Assay Detail
Functional
CHEMBL660753
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Concentration required for 50% Inhibition against Cholesteryl ester transfer protein (CETP) mediated transfer in cholesterol fed hamster serum
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Tissue | Serum |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Chiral N,N-disubstituted trifluoro-3-amino-2-propanols are potent inhibitors of cholesteryl ester transfer protein.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.92 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL297971 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL297971 | — | IC50 | = | 12000.0 | nM | 4.92 |