Assay Detail
Binding
CHEMBL660941
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was evaluated for inhibition against the GC1 extended spectrum Class C beta-lactamase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
The synthesis and evaluation of 3-substituted-7-(alkylidene)cephalosporin sulfones as beta-lactamase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.70 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL355558 | — | — | 1 | 7.92 |
| CHEMBL1439 | TAZOBACTAM SODIUM | 4.0 | 1 | 5.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL355558 | — | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL1439 | TAZOBACTAM SODIUM | IC50 | = | 3400.0 | nM | 5.47 |