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Assay Detail

CHEMBL661386

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
In vitro inhibition of crude dog red blood cell carbonic anhydrase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Canis lupus familiaris
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Carbonic anhydrase (CHEMBL2095180)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Sulfonylmethanesulfonamide inhibitors of carbonic anhydrase.
Scholz TH, Sondey JM, Randall WC, Schwam H, Thompson WJ, Mallorga PJ, Sugrue MF, Graham SL.
J Med Chem (1993) 36 : 2134 -2141
PubMed 8340917 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.70 5.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL27601 BENZENESULFONAMIDE 1 5.70
CHEMBL69291 ETHANESULFONIC ACID AMIDE 1 -
CHEMBL305268 METHANESULFONAMIDE 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL27601 BENZENESULFONAMIDE IC50 = 2000.0 nM 5.70
CHEMBL69291 ETHANESULFONIC ACID AMIDE IC50 = 1000000.0 nM -
CHEMBL305268 METHANESULFONAMIDE IC50 = 1000000.0 nM -