Assay Detail
Binding
CHEMBL661664
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards Rabbit Coagulation factor X in a rabbit arterio-venous (A-V) shunt model
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Synthesis and SAR of benzamidine factor Xa inhibitors containing a vicinally-substituted heterocyclic core.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 10.01 | 10.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL152854 | — | — | 1 | 10.52 |
| CHEMBL156924 | — | — | 1 | 10.10 |
| CHEMBL153611 | — | — | 1 | 9.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL152854 | — | Ki | = | 0.03 | nM | 10.52 |
| CHEMBL156924 | — | Ki | = | 0.08 | nM | 10.10 |
| CHEMBL153611 | — | Ki | = | 0.4 | nM | 9.40 |