Assay Detail
Binding
CHEMBL661876
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Compound was evaluated for its inhibitory activity against human cathepsin G
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Inhibition of serine proteases: activity of 1,3-diazetidine-2,4-diones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.06 | 9.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL47394 | — | — | 1 | 9.41 |
| CHEMBL296771 | — | — | 1 | 8.64 |
| CHEMBL298276 | — | — | 1 | 6.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL47394 | — | IC50 | = | 0.39 | nM | 9.41 |
| CHEMBL296771 | — | IC50 | = | 2.3 | nM | 8.64 |
| CHEMBL298276 | — | IC50 | = | 740.0 | nM | 6.13 |