Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL662157

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound concentration that causes 50 % inhibition of binding of specific radioligand to human CCR3 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

C-C chemokine receptor type 3 (CHEMBL3473)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 2: structure-activity relationships for substituted 2-Aryl-1-[N-(methyl)-N-(phenylsulfonyl)amino]-4-(piperidin-1-yl)butanes.
Finke PE, Meurer LC, Oates B, Mills SG, MacCoss M, Malkowitz L, Springer MS, Daugherty BL, Gould SL, DeMartino JA, Siciliano SJ, Carella A, Carver G, Holmes K, Danzeisen R, Hazuda D, Kessler J, Lineberger J, Miller M, Schleif WA, Emini EA.
Bioorg Med Chem Lett (2001) 11 : 265 -270
PubMed 11206474 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL83338 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL83338 IC50 = 10000.0 nM 5.00