Assay Detail
Functional
CHEMBL662209
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested in vitro for growth inhibition of Chinese Hamster Ovary(CHO) cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Cell Type | CHO |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
N-(5,5-diacetoxypent-1-yl)doxorubicin: a new intensely potent doxorubicin analogue.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.74 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL111208 | — | — | 1 | 9.40 |
| CHEMBL321868 | — | — | 1 | 7.24 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 7.22 |
| CHEMBL326683 | — | — | 1 | 7.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL111208 | — | IC50 | = | 0.4 | nM | 9.40 |
| CHEMBL321868 | — | IC50 | = | 57.0 | nM | 7.24 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL326683 | — | IC50 | = | 83.0 | nM | 7.08 |