Assay Detail
Functional
CHEMBL662210
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The compound was tested in vitro for growth inhibition of subline (CHO/DOX) with acquired resistance to doxorubicin
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Cell Type | CHO |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
N-(5,5-diacetoxypent-1-yl)doxorubicin: a new intensely potent doxorubicin analogue.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.80 | 9.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL111208 | — | — | 1 | 9.15 |
| CHEMBL326683 | — | — | 1 | 6.46 |
| CHEMBL321868 | — | — | 1 | 6.38 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 5.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL111208 | — | IC50 | = | 0.7 | nM | 9.15 |
| CHEMBL326683 | — | IC50 | = | 350.0 | nM | 6.46 |
| CHEMBL321868 | — | IC50 | = | 420.0 | nM | 6.38 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 6000.0 | nM | 5.22 |