Assay Detail
Binding
CHEMBL662422
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for the inhibition of specific binding of [125I]bolton Hunter CCK-8 to Cholecystokinin type A receptor in the rat pancreas
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Cholecystokinin receptor type A (CHEMBL2871) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Diastereoselective synthesis of cyclopropyl phenylalanines and their incorporation into dipeptides
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.60 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL269098 | — | — | 1 | 10.00 |
| CHEMBL349079 | — | — | 1 | 7.58 |
| CHEMBL159138 | — | — | 1 | 7.22 |
| CHEMBL349473 | — | — | 1 | 7.08 |
| CHEMBL158547 | — | — | 1 | 6.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL269098 | — | IC50 | = | 0.1 | nM | 10.00 |
| CHEMBL349079 | — | IC50 | = | 26.0 | nM | 7.58 |
| CHEMBL159138 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL349473 | — | IC50 | = | 84.0 | nM | 7.08 |
| CHEMBL158547 | — | IC50 | = | 720.0 | nM | 6.14 |