Assay Detail
Binding
CHEMBL662446
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Binding affinity of compound toward human Coagulation factor X was evaluated
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Molecular structures of human factor Xa complexed with ketopiperazine inhibitors: preference for a neutral group in the S1 pocket.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 8.63 | 9.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL110419 | — | — | 1 | 9.05 |
| CHEMBL423417 | — | — | 1 | 8.96 |
| CHEMBL48813 | — | — | 1 | 8.89 |
| CHEMBL157813 | — | — | 1 | 8.52 |
| CHEMBL351298 | — | — | 1 | 7.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL110419 | — | Ki | = | 0.9 | nM | 9.05 |
| CHEMBL423417 | — | Ki | = | 1.1 | nM | 8.96 |
| CHEMBL48813 | — | Ki | = | 1.3 | nM | 8.89 |
| CHEMBL157813 | — | Ki | = | 3.0 | nM | 8.52 |
| CHEMBL351298 | — | Ki | = | 18.0 | nM | 7.75 |