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Assay Detail

CHEMBL662447

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity towards Coagulation factor X
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Coagulation factor X (CHEMBL244)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Optimization of a screening lead for factor VIIa/TF.
Young WB, Kolesnikov A, Rai R, Sprengeler PA, Leahy EM, Shrader WD, Sangalang J, Burgess-Henry J, Spencer J, Elrod K, Cregar L.
Bioorg Med Chem Lett (2001) 11 : 2253 -2256
PubMed 11527709 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.30 9.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL73737 1 9.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL73737 Ki = 0.5 nM 9.30