Assay Detail
Binding
CHEMBL662822
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Binding affinity on Coagulation factor X
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Crystal structures of human factor Xa complexed with potent inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.40 | 9.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL330572 | — | — | 1 | 9.15 |
| CHEMBL110419 | — | — | 1 | 9.05 |
| CHEMBL275368 | — | — | 1 | 7.75 |
| CHEMBL316053 | — | — | 1 | 7.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL330572 | — | Ki | = | 0.7 | nM | 9.15 |
| CHEMBL110419 | — | Ki | = | 0.9 | nM | 9.05 |
| CHEMBL275368 | — | Ki | = | 18.0 | nM | 7.75 |
| CHEMBL316053 | — | Ki | = | 22.0 | nM | 7.66 |