Assay Detail
Binding
CHEMBL662864
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for the inhibition of specific binding of [125I]bolton Hunter CCK-8 to Cholecystokinin type B receptor in mouse cerebral cortex
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Cerebral cortex |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Gastrin/cholecystokinin type B receptor (CHEMBL2854) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Diastereoselective synthesis of cyclopropyl phenylalanines and their incorporation into dipeptides
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.47 | 9.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL269098 | — | — | 1 | 9.52 |
| CHEMBL349079 | — | — | 1 | 8.41 |
| CHEMBL159138 | — | — | 1 | 7.27 |
| CHEMBL349473 | — | — | 1 | 6.85 |
| CHEMBL158491 | — | — | 1 | 6.57 |
| CHEMBL158547 | — | — | 1 | 6.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL269098 | — | IC50 | = | 0.3 | nM | 9.52 |
| CHEMBL349079 | — | IC50 | = | 3.9 | nM | 8.41 |
| CHEMBL159138 | — | IC50 | = | 54.0 | nM | 7.27 |
| CHEMBL349473 | — | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL158491 | — | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL158547 | — | IC50 | = | 600.0 | nM | 6.22 |