Assay Detail
Binding
CHEMBL662872
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Binding affinity against Coagulation factor X
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Protease inhibitors: current status and future prospects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.71 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL73193 | FIDEXABAN | 2.0 | 1 | 10.00 |
| CHEMBL20240 | YM-60828 | — | 1 | 8.89 |
| CHEMBL418849 | — | — | 1 | 7.58 |
| CHEMBL19902 | DX-9065A | — | 1 | 7.39 |
| CHEMBL1201881 | SEPIMOSTAT MESYLATE | — | 1 | 4.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL73193 | FIDEXABAN | Ki | = | 0.1 | nM | 10.00 |
| CHEMBL20240 | YM-60828 | Ki | = | 1.3 | nM | 8.89 |
| CHEMBL418849 | — | Ki | = | 26.0 | nM | 7.58 |
| CHEMBL19902 | DX-9065A | Ki | = | 41.0 | nM | 7.39 |
| CHEMBL1201881 | SEPIMOSTAT MESYLATE | Ki | = | 20400.0 | nM | 4.69 |