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Assay Detail

CHEMBL663262

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against Coagulation factor Xa
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Coagulation factor X (CHEMBL244)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Development of irreversible diphenyl phosphonate inhibitors for urokinase plasminogen activator.
Joossens J, Van der Veken P, Lambeir AM, Augustyns K, Haemers A.
J Med Chem (2004) 47 : 2411 -2413
PubMed 15115382 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.15 4.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL311067 1 4.19
CHEMBL80844 1 4.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL311067 IC50 = 65000.0 nM 4.19
CHEMBL80844 IC50 = 79000.0 nM 4.10