Assay Detail
Binding
CHEMBL663268
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Compound was evaluated for the binding affinity against human Coagulation factor Xa
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Noncovalent tripeptidic thrombin inhibitors incorporating amidrazone, amine and amidine functions at P1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 5.85 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL268640 | — | — | 1 | 6.92 |
| CHEMBL7440 | — | — | 1 | 6.71 |
| CHEMBL7860 | — | — | 1 | 6.70 |
| CHEMBL269575 | — | — | 1 | 6.52 |
| CHEMBL7895 | — | — | 1 | 6.44 |
| CHEMBL451242 | — | — | 1 | 5.30 |
| CHEMBL414606 | — | — | 1 | 4.23 |
| CHEMBL8079 | — | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL268640 | — | Ki | = | 120.0 | nM | 6.92 |
| CHEMBL7440 | — | Ki | = | 193.0 | nM | 6.71 |
| CHEMBL7860 | — | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL269575 | — | Ki | = | 300.0 | nM | 6.52 |
| CHEMBL7895 | — | Ki | = | 360.0 | nM | 6.44 |
| CHEMBL451242 | — | Ki | = | 5000.0 | nM | 5.30 |
| CHEMBL414606 | — | Ki | = | 59000.0 | nM | 4.23 |
| CHEMBL8079 | — | Ki | = | 100000.0 | nM | 4.00 |