Assay Detail
Binding
CHEMBL663591
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Binding affinity towards opioid Delta receptor using [3H]DADLE as radioligand
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Optically pure (-)-4-[(N-allyl-3-methyl-4-piperidinyl)phenyl-amino]-N,N-diethylbenzami de displays selective binding and full agonist activity for the delta opioid receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 8.17 | 9.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL25230 | — | — | 1 | 9.04 |
| CHEMBL13470 | SNC-80 | — | 1 | 8.80 |
| CHEMBL102497 | — | — | 1 | 8.25 |
| CHEMBL115730 | — | — | 1 | 7.92 |
| CHEMBL22650 | — | — | 1 | 6.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL25230 | — | Ki | = | 0.91 | nM | 9.04 |
| CHEMBL13470 | SNC-80 | Ki | = | 1.57 | nM | 8.80 |
| CHEMBL102497 | — | Ki | = | 5.58 | nM | 8.25 |
| CHEMBL115730 | — | Ki | = | 11.9 | nM | 7.92 |
| CHEMBL22650 | — | Ki | = | 139.0 | nM | 6.86 |