Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL663592

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was evaluated for the binding affinity towards delta-opioid receptor by displacement of [3H]p-CI-DPDPE radioligand from mouse vas deferens
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Vas deferens
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Delta-type opioid receptor (CHEMBL3222)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

The stereochemical requirements of the novel -opioid selective dipeptide antagonist TMT-Tic
Liao S, Lin J, Shenderovich MD, Han Y, Hasohata K, Davis P, Qiu W, Porreca F, Yamamura HI, Hruby VJ
Bioorg Med Chem Lett (1997) 7 : 3049 -3052
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.72 6.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL485576 1 6.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL485576 Ki = 191.0 nM 6.72