Assay Detail
Functional
CHEMBL663909
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for its relaxation activity on smooth muscle of canine mesenteric artery
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Canis lupus familiaris |
| Tissue | Artery |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Benzopyran sulfoxide derivatives as New potassium channel activator
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 6.04 | 7.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL152370 | — | — | 1 | 7.21 |
| CHEMBL97196 | — | — | 1 | 6.65 |
| CHEMBL49035 | CROMAKALIM | 2.0 | 1 | 5.71 |
| CHEMBL151571 | — | — | 1 | 5.71 |
| CHEMBL348665 | — | — | 1 | 4.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL152370 | — | EC50 | = | 61.8 | nM | 7.21 |
| CHEMBL97196 | — | EC50 | = | 222.0 | nM | 6.65 |
| CHEMBL49035 | CROMAKALIM | EC50 | = | 1960.0 | nM | 5.71 |
| CHEMBL151571 | — | EC50 | = | 1960.0 | nM | 5.71 |
| CHEMBL348665 | — | EC50 | = | 12200.0 | nM | 4.91 |