Assay Detail
Binding
CHEMBL664334
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of rat ovarian microsomal Cytochrome P450 19A1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Pyridyl-substituted tetrahydrocyclopropa[a]naphthalenes: highly active and selective inhibitors of P450 arom.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.90 | 6.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL294361 | — | — | 1 | 6.58 |
| CHEMBL488 | AMINOGLUTETHIMIDE | 4.0 | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL294361 | — | IC50 | = | 265.0 | nM | 6.58 |
| CHEMBL488 | AMINOGLUTETHIMIDE | IC50 | = | 6200.0 | nM | 5.21 |