Assay Detail
Binding
CHEMBL664468
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against DNA topoisomerase I
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Quantized surface complementarity diversity (QSCD): a model based on small molecule-target complementarity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.20 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13935 | — | — | 1 | 7.55 |
| CHEMBL13998 | — | — | 1 | 6.84 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13935 | — | IC50 | = | 28.0 | nM | 7.55 |
| CHEMBL13998 | — | IC50 | = | 143.0 | nM | 6.84 |