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Assay Detail

CHEMBL665446

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against dihydrofolate reductase in rat.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Dihydrofolate reductase (CHEMBL2363)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.
Queener SF.
J Med Chem (1995) 38 : 4739 -4759
PubMed 7490723 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.72 4.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL357573 1 4.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL357573 IC50 = 18900.0 nM 4.72