Assay Detail
Binding
CHEMBL665833
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In vitro inhibitory activity against Cyclooxygenase was determined
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Conversion of NSAIDS into balanced dual inhibitors of cyclooxygenase and 5-lipoxygenase
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.25 | 6.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL350729 | — | — | 1 | 6.72 |
| CHEMBL298672 | — | — | 1 | 6.57 |
| CHEMBL50833 | — | — | 1 | 6.21 |
| CHEMBL54156 | — | — | 1 | 6.16 |
| CHEMBL299794 | — | — | 1 | 6.07 |
| CHEMBL417022 | — | — | 1 | 5.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL350729 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL298672 | — | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL50833 | — | IC50 | = | 610.0 | nM | 6.21 |
| CHEMBL54156 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL299794 | — | IC50 | = | 850.0 | nM | 6.07 |
| CHEMBL417022 | — | IC50 | = | 1750.0 | nM | 5.76 |